Technical Brief: Spray Dried Plasma Top-Dressing Significantly Reduces Mortality and Medication Use in Grow-Finish Pigs

Presented at the 2025 Leman Swine Conference (Download the PDF here

Overview

New research presented by APC demonstrates that top-dressing feed with 2 grams of spray dried plasma (SDP) per pig per day can offer a powerful, antibiotic-alternative health strategy in grow-finish systems. Conducted under commercial conditions in Brazil, the study measured mortality and injectable medication usage over a 98-day production period.

Objective

To evaluate whether low-dose, daily SDP application in grow-finish pigs could improve survival and reduce reliance on injectable antibiotic treatments.

Trial Design

  • Total pigs: 1,536 (castrated males and females)

  • Pens: 48 total (24 control, 24 SDP treatment)

  • Treatment: 2 g SDP/pig/day, hand-mixed on feed

  • Duration: 98 days (grow-finish phase)

  • Metrics: Mortality, antibiotic injections (Tulathromycin, Dexamethasone, Metamizole sodium), total medication use


Key Results

Metric Control SDP (2g/d) Improvement P-Value
Mortality per pen (number) 1.08 0.25 -77% 0.0007
Mortality (%) 3.39 0.78 -77% 0.0003
Tulathromycin injections/pen 0.75 0.13 -83% 0.0016
Total medications/pen 1.70 1.11 -35% trend 0.0877