Phileo By Lesaffre, Premium Yeast Probiotic: Largest Primary Fermentation in the World


Actisaf® Sc 47 HR+ is a concentrate of live yeast Saccharomyces cerevisiae processed in a microspherule form (Lesaffre proprietary strain: NCYC Sc 47 / CNCM I-4407).
This unique patented Actisaf® Sc 47 micro-spherule form has been developed to deliver unsurpassed intrinsic thermoresistance, without the need for any foreign material coating.

Actisaf® Sc 47 HR+ new generation is designed to withstand the main stress factors encountered by the yeast probiotic during pelleting process :

  • Compression & friction
  • Heat
  • Humidity

Compatibility with acids in the feed formula comes as the 4th constraint taken into consideration in this multifactorial approach.

Actisaf® Sc 47 HR+ new generation : from heat resistance to multifactorial resistance

As no feed mill is the same and no process is identical, throughout the years Phileo accumulated extensive feed technology expertise. Since all these different constraints have to be considered globally and not individually, we are focusing on new indicators, which are closer to the real pelleting constraints and take into account the interactions between process parameters:

  • Specific Thermal Energy
  • Specific Mechanical Energy
  • Contact time in mash feed


Feed tech Service is a complete service to support feed manufacturers

To support customers facing the challenges of today’s production processes, dedicated Phileo R&D teams together with a network of industry experts led to the creation of Feed tech Service. Feed tech Service gives customers a clear view of the multifactorial resistance of Actisaf® yeast probiotic in the feed under their given pelleting conditions.

Meta data analysis of more than 2000 feed analyses done on an annual basis are the backbone of a newly developed numerical platform. This digital platform gathers the already existing Phileo expertise in feed technology, with the target to share it with the customers and help them develop their activity.

Key benefits Actisaf® Sc 47 HR+ new generation

Dairy cattle

Cow, goat, ewe, buffalo

↓ ruminal acidosis
↑ milk yield
↑ milk solids

Cattle for fattening

Beef, lamb

↓ ruminal acidosis
↑ average daily gain
↑ feed efficiency

Gestating and lactating mare

↑ colostrum and milk immunological and nutritional properties
↑ immune acquisition by the foal at birth

Adult horse

↑ digestive comfort and welfare
↑ body condition
↑ recovery

Gestating and lactating sow

↓ sow body weight loss during lactation
↑ IgG content and nutritional quality of colostrum
↑ IgA content and nutritional quality of milk
↓ risk of neonatal diarrhoea in suckling piglets
↑ litter weight at weaning

Fattening pig

↑ average daily gain
↑ feed efficiency
↓ intestinal disorders
↑ carcass quality

Fattening rabbit

↓ mortality
↑ average daily gain

Mode of action Actisaf® Sc 47 HR+ new generation


  • Strengthens the reducing power of rumen:
    • ↑ lactate-utilizing bacteria
    • ↑ cellulolytic bacteria
  • Improves fiber digestion
  • Increases rumen pH by avoiding the build up of lactic acid


  • Improves and stabilises microflora balance
  • Improves fiber digestibility
  • Increases production of Volatile Fatty Acids
  • Limits pathogen multiplication and adhesion on the enterocytes
  • Reduces intestinal inflammation
  • Decreases E. coli shedding


  • Improves microflora balance in the caecum
  • Enhances fiber digestibility
  • Limits overproduction and accumulation of lactic acid in the caecum


  • Improves microflora balance in the caecum
  • Enhances fiber digestibility


  • 25 kg polyethylene bag
  • 1000 kg polypropylene woven big bag with inside polyethylene liner

EU Registration

EU registration number: 4b 1702
Category: Zootechnical additives – Gut flora stabilisers or digestibility enhancers.

The information provided in this document is at the best of our knowledge, true and accurate. However, products must only be used in compliance with local laws and regulations and we cannot guarantee freedom of use for every intended application or country.

Other forms

Live yeast concentrate - Actisaf INST

  • Non-pelleted feed
  • Liquid feed