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Managing PRRS

Porcine reproductive and respiratory syndrome (PRRS) continues to negatively impact the pork industry. While there has been a reduction in overall cost to the pork industry, it remains a costly disease challenge requiring on-going research to better understand overall impacts as well as innovation to mitigate the challenge.

Proven PRRS Solutions

Controlling PRRS requires diligent biosecurity measures, a focus on growing the healthiest pigs and a strong protocol that involves planning ahead  and being prepared for challenges. Elanco offers both an effective vaccination against PRRS and a solution for swine respiratory disease (SRD) associated with Mycoplasma hyopneumoniae (Myco) in the presence of PRRS. 
Prevacent® PRRS: PRRS Control from Start to Finish

PRRS increases mortality and reduces growth performance of wean-to-finish pigs. PRRS may also cause an increase in the number of premature farrowings, late term abortions, stillborn piglets and mummified fetuses.1

Prevacent has proven effective against the respiratory form of PRRS in healthy pigs at least 2 weeks of age or older and against reproductive disease when vaccinated 6 weeks prior to breeding.

With no reduction in growth performance or an impact on farrowing as a result of vaccination, Prevacent is a safe and effective solution for PRRS control across production segments.2, 3
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Pulmotil® AC: PRRS-induced SRD Control

Pulmotil AC quickly and effectively manages swine respiratory disease (SRD) associated with Mycoplasma hyopneumoniae (Myco) in the presence
of PRRS without the need to formulate new rations, or invest the additional time, individual documentation and repeated injection associated with
                   individual pig injections.

Porcine reproductive and respiratory syndrome virus (PRRSv) impairs natural disease-fighting macrophages, increasing susceptibility to other bacteria. Pulmotil’s unique mode of action concentrates in pulmonary macrophages, slowing the effeciveness of the PRRSv replication process and killing bacteria associated with SRD.4, 5

Pulmotil AC is the only FDA-approved aqueous concentrate that controls SRD associated with Myco in the presence of PRRSv in groups of swine in buildings where a respiratory disease outbreak is diagnosed.6

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*Must be diluted before administration to animals. Use within 24 hours of mixing with water.
**Intake assumptions: 25 lb pig = 2.5 lbs/day feed, 0.3 gal/day water; 50 lb pig = 3 lbs/day feed, 0.6 gal/day water; 75 lb pig = 4 lbs/day feed, 0.9 gal/day water.
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The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.
For Pulmotil AC: Before using this product it is important to read the entire product insert, including the boxed human warning.


Exposure to tilmicosin in humans has been associated with chest pain, increased heart rate, dizziness, headache, and nausea. Death has been reported following ingestion or injection of tilmicosin. Avoid direct skin and eye contact. In case of human exposure, call 1-800-722-0987, and consult a physician immediately.
  • Wear overall, impervious gloves and eye protection when mixing and handling the product. Wash hands after handling the product. 
  • Wash affected parts if skin contact occurs. If accidental eye contact occurs, immediately rinse thoroughly with water.
  • Caution: Pulmotil AC is to be used by, or on the order of, a licensed veterinarian.
  • For use only in swine. Not for injection. Injection of tilmicosin has been shown to be fatal in swine and non-human primates, and may be fatal in horses and goats.
  • Swine intended for human consumption must not be slaughtered within 7 days of treatment.
  • Always treat the fewest number of animals necessary to control a respiratory disease outbreak. Prescriptions shall not be refilled.
  • Concurrent use of Pulmotil AC and another macrolide by any route, or use of another macrolide immediately following this use of Pulmotil AC is not advised.
  • Ensure that pigs have continuous access to medicated water during the treatment period. Monitor pigs for signs of water refusal and dehydration while being treated.

1Iowa State University. Porcine Reproductive and Respiratory Syndrome (PRRS). Available at: Accessed on September 20, 2019.
2Elanco Animal Health. Data on file.
3Elanco Animal Health. Data on file.
4Rossow, K.D. 1998. South Dakota State University. Porcine reproductive and respiratory syndrome. The American College of Veterinary Pathologists 35: 1-20.
5Blais, J. 1994. Intracellular accumulation of tilmicosin in primary swine alveolar macrophages. Food and Agriculture Organization of the United Nations.
6VanAlstine, W. 2012. “Respiratory System.” Disease of Swine 10th ed.: 348-362. 

Prevacent, Pulmotil, Elanco, the Full Value Pork logoElanco logo and the diagonal bar logo are trademarks of Elanco or its affiliates.
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PM-US-20-1332(2) | 607274362