How Plasma is Made

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Learn About APC & Plasma

Second in a Series

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How Plasma is Made

Plasma is the clear liquid portion of blood that remains after red blood cells, white blood cells and platelets are removed. Plasma contains a complex mixture of active functional proteins that help support and maintain normal immune function during times of stress.

The process of making spray-dried plasma starts with whole blood from healthy pigs and cattle that is collected and pooled at federally inspected abattoirs. The blood is centrifuged to separate the red blood cells from the plasma. It is then shipped to APC’s dedicated processing facilities, which all follow Current Good Manufacturing Practices (CGMPs) and are Safe Feed / Safe Food certified (SFSF).

At the APC plant, the plasma is filtered and concentrated to remove excess liquid. The concentrated plasma undergoes photopurification using ultraviolet light energy* (UV-C) to inactivate potential viruses, bacteria, protozoa and parasites that may be present.

The plasma is then spray-dried to produce a dry powder and preserve thermally-sensitive proteins. Spray-drying is a critical point to inactivate pathogens and is conducted with specialized computer-controlled equipment. Finished plasma products are then packaged and stored at 20°C for a minimum of two weeks.

APC will then ship product to our customers so they may formulate plasma into swine diets. Plasma functional proteins are routinely included in the first phase diets of piglets to help them better cope with environmental stresses and in later feeds to support sows during gestation and lactation.

*Denison, IA Porcine and Sublette, KS Bovine facilities

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